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Chi-Yuan Chen Selected Research

cryptopleurine

8/2012Antitumor agents 295. E-ring hydroxylated antofine and cryptopleurine analogues as antiproliferative agents: design, synthesis, and mechanistic studies.
7/2011Antitumor agents 288: design, synthesis, SAR, and biological studies of novel heteroatom-incorporated antofine and cryptopleurine analogues as potent and selective antitumor agents.

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Chi-Yuan Chen Research Topics

Disease

29Neoplasms (Cancer)
05/2022 - 11/2009
9Hepatocellular Carcinoma (Hepatoma)
09/2021 - 07/2016
9Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2021 - 03/2014
5Squamous Cell Carcinoma of Head and Neck
09/2021 - 11/2009
4Liver Neoplasms (Liver Cancer)
09/2021 - 12/2019
4Lung Neoplasms (Lung Cancer)
01/2021 - 01/2013
4Carcinogenesis
04/2020 - 08/2012
4Adenocarcinoma of Lung
04/2016 - 08/2012
3Infections
01/2022 - 10/2010
3Inflammation (Inflammations)
09/2021 - 02/2017
3Neoplasm Metastasis (Metastasis)
01/2018 - 02/2014
2Breast Neoplasms (Breast Cancer)
09/2021 - 11/2011
2Skin Neoplasms (Skin Cancer)
01/2018 - 01/2017
2Influenza in Birds (Avian Flu)
03/2013 - 11/2010
1Mouth Neoplasms (Oral Cancer)
03/2022
1Psoriasis (Pustulosis Palmaris et Plantaris)
06/2018
1Abscess
06/2018
1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
11/2017
1Leukemia
11/2017
1Hypoxia (Hypoxemia)
12/2016
1Lymphoma (Lymphomas)
04/2016

Drug/Important Bio-Agent (IBA)

8Proteins (Proteins, Gene)FDA Link
01/2022 - 11/2010
8ErbB Receptors (EGF Receptor)IBA
01/2021 - 01/2013
6Long Noncoding RNAIBA
01/2019 - 07/2016
4hydroxygenkwaninIBA
09/2021 - 12/2019
4Tyrosine Kinase InhibitorsIBA
01/2021 - 03/2014
4Pharmaceutical PreparationsIBA
11/2017 - 09/2012
4VaccinesIBA
03/2013 - 01/2007
3magnololIBA
01/2020 - 01/2017
3RNA (Ribonucleic Acid)IBA
01/2019 - 08/2017
3MelatoninIBA
09/2018 - 10/2017
2LigandsIBA
11/2020 - 06/2018
2Heterogeneous-Nuclear Ribonucleoproteins (Informatin)IBA
04/2020 - 03/2016
2Histone Deacetylases (Histone Deacetylase)IBA
01/2020 - 01/2020
2MicroRNAs (MicroRNA)IBA
12/2019 - 09/2018
2sulforaphaneIBA
11/2019 - 06/2015
2hnRNP A2IBA
03/2019 - 02/2014
2Telomerase (Telomerase Reverse Transcriptase)IBA
03/2019 - 09/2012
2Heterogeneous Nuclear Ribonucleoprotein A1IBA
03/2019 - 03/2016
2growth arrest specific transcript 5IBA
01/2019 - 01/2018
2Etoposide (VP 16)FDA LinkGeneric
09/2018 - 01/2018
2corylinIBA
01/2018 - 01/2018
2maleimideIBA
11/2017 - 09/2012
2Protein Isoforms (Isoforms)IBA
03/2016 - 01/2013
2Hemagglutinins (Hemagglutinin)IBA
03/2013 - 11/2010
2cryptopleurineIBA
08/2012 - 07/2011
2antofineIBA
08/2012 - 07/2011
1Phosphotransferases (Kinase)IBA
05/2022
1TriterpenesIBA
03/2022
1Nuclear Localization Signals (Nuclear Localization Signal)IBA
01/2022
1Clodronic Acid (Clodronate)IBA
09/2021
1Liposomes (Liposome)IBA
09/2021
1Doxorubicin (Adriamycin)FDA LinkGeneric
09/2021
1palbociclibIBA
09/2021
1Cyclin-Dependent Kinases (cdk Proteins)IBA
09/2021
1Irinotecan (Camptosar)FDA LinkGeneric
04/2021
1CurcuminIBA
04/2021
1brigatinibIBA
01/2021
1QuercetinIBA
01/2021
1Pemetrexed (MTA)FDA Link
11/2020
1Immune Checkpoint InhibitorsIBA
11/2020
1Histone Deacetylase InhibitorsIBA
01/2020
1Sorafenib (BAY 43-9006)FDA Link
01/2020
1Forkhead Transcription Factors (Forkhead Box Proteins)IBA
12/2019
1FlavonoidsIBA
12/2019
1Reactive Oxygen Species (Oxygen Radicals)IBA
11/2019
1Imiquimod (Aldara)FDA LinkGeneric
06/2018
1anthranilic acid (anthranilate)IBA
06/2018
1Benzoates (Benzoate)IBA
06/2018
1CXC ChemokinesIBA
06/2018
1ChemokinesIBA
06/2018
1CytokinesIBA
06/2018
1matrigelIBA
01/2018
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
11/2017
1Caspase 3 (Caspase-3)IBA
11/2017
1PolyphenolsIBA
02/2017
1SaltsIBA
04/2016
1RNA Precursors (Precursor, mRNA)IBA
03/2016
1RNA Splicing FactorsIBA
03/2016
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
06/2015
1Cycloheximide (Cicloheximide)IBA
01/2015
1Catalytic DNA (Deoxyribozyme)IBA
03/2014
1CholesterolIBA
03/2014
1triethylene glycolIBA
03/2014
1AfatinibIBA
03/2014
1phenanthreneIBA
02/2014
1Antineoplastic Agents (Antineoplastics)IBA
02/2014
1tylophorineIBA
02/2014
1CateninsIBA
08/2012
1HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
11/2011
1Biomarkers (Surrogate Marker)IBA
11/2011
1Antiviral Agents (Antivirals)IBA
11/2011
1Oxygen (Dioxygen)IBA
10/2010

Therapy/Procedure

4Therapeutics
04/2021 - 11/2011
3Drug Therapy (Chemotherapy)
09/2021 - 01/2018
2Radiotherapy
09/2021 - 09/2018
2Heterologous Transplantation (Xenotransplantation)
11/2009 - 11/2009
1Adjuvant Chemotherapy
09/2021
1Bioreactors (Bioreactor)
10/2010
1Artificial Respiration (Mechanical Ventilation)
05/2010